SupelMIP™ Amphetamines

- A Class-selective SPE sorbent for extraction of amphetamine related drugs (Amphetamine, Methamphetamine, Phentermine, MDA, MDMA and MDEA) from biological samples e.g. urine and saliva

Background

Amphetamine related drugs are currently among the most well-known psychotropic drugs of abuse and are used in sport, in the workplace and by recreational users. For, clinical and doping control SupelMIP™ SPE-Amphetamine drugs provide a simple, fast and class selective solid-phase extraction (SPE) procedure.The high senstivity of the SPE method using this product makes it particularly useful in forensic applications where low level detection may be required. SupelMIP™ Amphetamines provides:

• Class selective extraction
• Lower detection limits
• Improved MS-compatibility

Features and applications

Amphetamine, Methamphetamine, Phentermine, MDA (3,4-Methylenedioxyamphetamine), MDMA (3,4-methylenedioxy-N-methamphetamine) and MDEA (3,4-methylenedioxy-N-ethylamphetamine) are all extracted from biological samples e.g. urine and saliva with high recoveries, with detection levels in the pg/mL range and with minimized matrix effects.

It is also possible to use the SupelMIP™ Amphetamines cartridges in automated solid-phase extraction systems. A data sheet for extraction of Amphetamine related drugs from urine with LC-MS/MS detection is available.

Code	Sorbent mass	Column volume	Columns/box	Order
53228-U	25 mg	3 ml	50	www.sigmaaldrich.com

Literature

• Simple, Fast and Class Selective Extraction of Amphetamine and Related Drugs from Urine using Molecularly Imprinted Polymer (MIP) SPE and LC/MS/MS, Widstrand C, Bergström S, Wihlborg A, Supelco Technical Report, id. T407148
   Sigma-Aldrich Technical Report