Applications

Analytical scale

Solid-phase extraction (SPE) for trace analysis from complex matrices
Products, developed and produced by MIP Technologies and sold under the name SupelMIP™ by Supelco/Sigma-Aldrich, are currently available for specific analysis of chloramphenicol, tobacco specific nitrosamine derivatives, NNAL, triazines, riboflavin, clenbuterol, beta-agonists, beta-blockers and full beta receptor. These products serve control, analytical or contract research laboratories operating in the following sectors:

• Pharma
• Food & beverage
• Forensic
• Doping control
• Health
• Veterinary
• Environmental

MIP Technologies can also custom develop MIPs for most types of target molecule(s).

Process scale

MIP Technologies' process materials can be engineered for a large variety of molecules including:

• Small molecules
• Chiral compounds
• Proteins (via epitope imprinting)
• Peptides
• Carbohydrates

Selectivity towards one specific molecule or a class of related molecules can be designed into the MIP phase. Example of application areas:

• Pharmaceuticals
• Foods
• Chemicals
• Consumer products
• Environmental clean-up

MIP Technologies' process materials introduce selectivity into the separation/extraction process. It is possible to extract unwanted chemical compounds from complex mixtures, leading to a significantly increased productivity by decreasing the number of purification cycles which in turn leads to a more cost efficient process.

Increased Productivity by Molecularly Imprinted Polymers

The diagram shows a 25 times higher product capacity in unit mass/liter per hour using a MIP phase compared with a conventional resin.

MIP[4] Process™ is particularly advantageous in the intermediate and/or polishing steps of the purification cycle, where resolution is an important factor. As the diagram shows, MIPs can dramatically increase the productivity of a process due to their selectivity compared with conventional resins