Literature

Technical Magazines

Efficient Extraction of Toxic Compounds From Complex Matrices Using Molecularly Imprinted Polymers
 American Laboratory, Oct 2007

Selective Extractions by Molecularly Imprinted Polymers (MIPs).
 The Column, Feb 2006

Analysis of analytes - The use of MIPs in solid-phase extraction increases efficiency and improves detection limits.
 Laboratory News, June 2006

Molecularly Imprinted Polymers: A New Generation of Affinity Matrices.
 American Laboratory, Oct 2006

MIP Review articles and books

• Molecularly Imprinted Polymers, Man-Made Mimics of Antibodies and Their Applications in Analytical Chemistry (edited by B. Sellergren, Elsevier, Amsterdam, The Netherlands (2001))
• The emerging technique of molecular imprinting and its future impact on biotechnology. K. Mosbach and O. Ramström Bio/Technol. 1996, 14, 163-170
• Molecularly Imprinted Materials - Science and Technology M. Yan and O. Ramström, Marcel Dekker, New York, 2005, ISBN 0-8247-5353-4
• Synthetic strategies for the generation of molecularly imprinted organic polymers, A. G. Mayes and M. J. Whitcombe, Advanced Drug Delivery Reviews 57 (2005) 1742-1778

Peer reviewed published trace analysis using SupelMIP cartridges

Chloramphenicol

• Development of an improved method for trace analysis of chloramphenicol using molecularly imprinted polymers. Boyd B, Björk H, Billing J, Shimelis O, Axelsson S, Leonora M, Yilmaz E, J. Chromatorgr. A (2007), in press.
• Advantages of Molecularly Imprinted Polymers LC-ESI-MS/MS for the Selective Extraction and Quantification of Chloramphenicol in Milk-Based Matrixes. Comparison with a Classical Sample Preparation. Rayane Mohamed, Janique Richoz-Payot, Eric Gremaud, Pascal Mottier, Ecevit Yilmaz, Jean-Claude Tabet,§ and Philippe A. Guy*, Nestlé Research Center, Nestec Limited, P.O. Box 44, Vers-Chez-Les-Blanc, 1000 Lausanne 26, Switzerland, MIP Technologies, Scheelevägen 22, Box 737, 22007 Lund, Sweden, and § Laboratoire de Chimie Structurale Organique et Biologique, CNRS UMR 7613, University Pierre et Marie Curie, 4 Place Jussieu, 75252 Paris cedex 05, France. Analytical Chemistry, In Press, Available online 15 November 2007

Clenbuterol

• Extraction of clenbuterol from calf urine using a molecularly imprinted polymer followed by quantification by high-performance liquid chromatography with UV detection. Blomgren A, Berggren C, Holmberg A, Larsson F, Sellergren B, Ensing K, J Chromatogr A (2002) 975, 157-64

Beta-agonist

• Evaluation of MISPE for the multi-residue extraction of beta-agonists from calves urine. Widstrand C, Larsson F, Fiori M, Civitareale C, Mirante S, Brambilla G. J Chromatogr B Analyt Technol Biomed Life Sci. (2004) May 5; 804(1): 85-91
• The analysis of beta-agonists in bovine muscle using molecular imprinted polymers with ion trap LCMS screening, Kootstra PR, CJPF Kuijpers, KL Wubs, D van Doorn, SS Sterk, LA van Ginkel and RW Stephany, (2005) Anal. Chim. Acta, 529:75-81
• Multi-residue liquid chromatography/tandem mass spectrometric analysis of beta-agonists in urine using molecular imprinted polymers. Van Hoof N, Courtheyn D, Antignac JP, Van de Wiele M, Poelmans S, Noppe H, De Brabander H, Rapid Communications in Mass Spectrometry Volume 19, (2005) Issue 19:2801-2808
• Evaluation of two different clean-up steps, to minimise ion suppression phenomena in ion trap liquid chromatography-tandem mass spectrometry for the multi-residue analysis of beta agonists in calves urine, Fiori M, Civitareale C, Mirante S., Magarò E, and Brambilla G, Anal. Chim. Acta, 529 (2005) 207-210

Beta blockers

• Trace level determination of beta-blockers in waste waters by highly selective molecular imprinted polymers (MIP) extraction followed by liquid chromatography-quadrupole-linear ion trap (Qq-LIT) mass spectrometry Meritxell Gros1, Tânia-Mara Pizzolato², Mira Petrovic1,^3*, Maria José López de Alda1 and Damià Barceló^{1 1}Department of Environmental Chemistry, IIQAB-CSIC, c/Jordi Girona 18-26, 08034 Barcelona, Spain ²Instituto de Química-Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9500, Porto Alegre, Brasil ³Institució Catalana de Recerca i Estudis Avançats (ICREA), Passeig Lluis Companys 23, 80010 Barcelona, Spain Journal of Chromatography A, In Press, Available online 23 October 2007

NNAL

• Analysis of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Urine by Extraction on a Molecularly Imprinted Polymer Column and Liquid Chromatography/Atmospheric Pressure Ionization Tandem Mass Spectrometry, Xia Y, McGuffey JE, Bhattacharyya S, Sellergren B, Yilmaz E, Wang L, and Bernert JT, Anal. Chem. 77 (2005) 7639-7645

Pharmaceutical applications

• Selective solid phase extraction of a drug lead compound using molecularly imprinted polymers prepared by the target analogue approach. Dirion B, Lanza F, Sellergren B, Chassaing C, Venn R, Berggren C, Chromatographica (2002) 56, 237-241
• Molecularly imprinted polymers for the determination of a pharmaceutical development compound in plasma using 96-well MISPE technology. Chassaing C, Stokes J, Venn R F, Lanza F, Sellergren B, Holmberg A, Berggren C, J. Chromatogr. B (2004) 804, 71-81

Poster presentations

 Selective extraction using molecularly imprinted polymera, Pittcon 2007, Chicago, USA.

 Analysis of β-agonists in liver and urine using molecular imprinted polymers and LC-MS/MS, National Food Administration, Uppsala, Sweden

 Screening of beta-agonists in bovine hair using Molecular Imprinted Polymers (MIPs) and LCMS, RIVM, Bilthoven, The Netherlands

 Trace level determination of β-blockers in natural water by highly selective molecularly imprinted polymer (MIP) extraction followed by Q-trap liquid chromatography-tandem-mass spectrometry.

 Analysis of the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Urine by SPE on a Molecularly Imprinted Polymer (MIP) column and LC MS/MS, CDC, Atlanta, US

 Cross-reactivity of Imprinted Polymers - The ExploraSep Concept, MIP2006, Cardiff, UK

 Removal of contaminants from complex matrices using molecularly imprinted polymers (MIPs), Analytica 2006, Munich, Germany